{"product_id":"now-same-400mg-30tabs","title":"NOW SAMe 400mg 30tabs","description":"  \u003cp\u003e\u003cfont color=\"#8000ff\" size=\"6\" face=\"Verdana\"\u003e\u003cstrong\u003eNOW SAMe\u003c\/strong\u003e\u003c\/font\u003e \u003cb\u003e\u003cfont color=\"#f38a00\" size=\"2\" face=\"Arial\"\u003e\u003cfont color=\"#f38a00\" size=\"2\" face=\"Arial\"\u003e\u003cfont color=\"#f38a00\" size=\"2\" face=\"Arial\"\u003e \u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/b\u003e\u003c\/p\u003e\r\n  \u003cp\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eHelps reduce pain associated with Osteoarthritis. \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eSAMe supplementation may be beneficial in osteoarthritis\u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003edue to its analgesic and anti-inflammatory effects. SAMe is widely used in Europe for \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003ethis purpose. NOW \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eSAMe is enteric-coated which makes it very well tolerated and  \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eprotects it from degradation. This formulation is also suitable for vegetarians and \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003evegans. It is our most potent SAMe formulation.\u003c\/font\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e\r\n  \u003cp\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eSAMe (S-adenosyl-L-methionine) is a naturally occurring \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003esubstance that is present in the cells of all living organisms. It is a direct metabolite of \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003ethe essential amino acid, L-methionine. S-adenosylmethionine (SAMe) is distributed \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003ethroughout virtually all body tissues and fluids. Concentrations are highest in \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003echildhood and decrease with age. SAMe plays an essential role in more than 100 \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003ebiochemical reactions. It contributes to the synthesis, activation and\/or metabolism of  \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003ehormones, neurotransmitters, nucleic acids, proteins and phospholipids. SAMe is \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eproduced in the body by adenosine triphosphate (ATP) activation of methionine. \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eDeficiencies of B12 and folate can result in decreased SAMe concentrations in the \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003ecentral nervous system. Preliminary evidence suggests SAMe might stimulate \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003earticular cartilage growth and repair, specifically chondrocyte proteoglycan synthesis. \u003c\/font\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eSAMe might also protect against cytokine-induced synovial cell damage.\u003c\/font\u003e \u003c\/p\u003e\u003cb\u003e\r\n    \u003c\/b\u003e\u003cp\u003e\u003cfont size=\"4\" face=\"Verdana\"\u003eDirections:\u003c\/font\u003e\u003c\/p\u003e\u003cfont color=\"#533690\" size=\"2\"\u003e\u003cfont color=\"#533690\" size=\"2\"\u003e\u003cfont color=\"#000000\" size=\"4\" face=\"Verdana\"\u003eAdult Dosage: Take 1 tablet, 3 times daily on an empty stomach. Use for \u003c\/font\u003e\u003cfont size=\"4\"\u003e\u003cfont face=\"Verdana\"\u003e\u003cfont color=\"#000000\"\u003ea minimum of 2 weeks to see beneficial effects. \u003cb\u003eRefrigerate after opening.\u003c\/b\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003cfont color=\"#533690\" size=\"2\"\u003e\u003cfont color=\"#533690\" size=\"2\"\u003e\u003cfont size=\"4\"\u003e\u003cfont face=\"Verdana\"\u003e\u003cfont color=\"#000000\"\u003e\u003cb\u003e\u003cfont color=\"#f38a00\" size=\"2\" face=\"Arial\"\u003e\u003cfont color=\"#f38a00\" size=\"2\" face=\"Arial\"\u003e\u003cfont color=\"#f38a00\" size=\"2\" face=\"Arial\"\u003e \r\n                    \u003cp\u003e\u003cfont color=\"#000000\" size=\"4\" face=\"Verdana\"\u003eIngredients (each tablet contains):\u003c\/font\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/b\u003e\r\n            \u003cp\u003eS-Adenosylmethionine (S-Adenosyl-L-Methionine Disulfate Tosylate)…400 mg\u003c\/p\u003e\n\u003cb\u003e\r\n              \u003c\/b\u003e\u003cp\u003eNon-Medicinal Ingredients:\u003c\/p\u003e\n\u003cfont color=\"#533690\" size=\"2\"\u003e\u003cfont color=\"#533690\" size=\"2\"\u003e\u003cfont color=\"#000000\" size=\"4\"\u003eCellulose, Croscarmellose Sodium, Magnesium \u003c\/font\u003e\u003cfont color=\"#000000\" size=\"4\"\u003eStearate (vegetable source), Silica, Stearic Acid (vegetable source), Citric Acid, \u003c\/font\u003e\u003cfont color=\"#000000\" size=\"4\"\u003eAscorbic Acid, Tablet Coating.\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e\u003c\/font\u003e","brand":"NOW","offers":[{"title":"Default Title","offer_id":33559277714,"sku":"14903","price":78.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0408\/7649\/products\/s14903.jpg?v=1493144168","url":"https:\/\/parisnaturalhealthfoods.ca\/products\/now-same-400mg-30tabs","provider":"Paris Natural Foods","version":"1.0","type":"link"}